SCHEMBL9355142

SCHEMBL9355142

C=C(CC(=O)Oc1ccccc1Br)C(=O)Oc1ccccc1Br

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.39
NPC1 O15118 2/20 0.39
GRM4 Q14833 3/20 0.39
KMT2A Q03164 5/20 0.38
HPGD P15428 3/20 0.38
MEN1 O00255 3/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 3/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 1/20 0.37
STAT3 P40763 1/20 0.37
STAT1 P42224 1/20 0.37
NCEH1 Q6PIU2 1/20 0.36
USP2 O75604 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355191 0.90 LMNA (0.38) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL689814 0.81 GAA (0.44) RAB9ANPC1KMT2AHPGDLMNA
SCHEMBL9355575 0.80 KMT2A (0.44) RAB9ANPC1KMT2AHPGDMEN1
SCHEMBL27145067 0.79 KDM4E (0.58) KMT2AHPGDMEN1LMNAKDM4E
SCHEMBL27720065 0.79 GRM4 (0.41) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL28210557 0.77 L3MBTL1 (0.40) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL1343624 0.75 ELANE (0.46) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL9661883 0.75 GRM4 (0.39) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL9034169 0.75 KMT2A (0.50) RAB9ANPC1GRM4KMT2AHPGD
SCHEMBL11599808 0.75 GRM4 (0.42) RAB9ANPC1GRM4KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP disclosed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US disclosed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP disclosed