SCHEMBL9355191

SCHEMBL9355191

C=C(CC(=O)Oc1ccccc1Br)C(=O)Oc1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 3/20 0.35
ELANE P08246 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MGLL Q99685 1/20 0.35
KMT2A Q03164 6/20 0.34
MEN1 O00255 4/20 0.34
RAB9A P51151 3/20 0.34
NPC1 O15118 2/20 0.34
NCEH1 Q6PIU2 1/20 0.34
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GRM4 Q14833 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355142 0.90 RAB9A (0.39) LMNASMN1; SMN2MAPTL3MBTL1KMT2A
SCHEMBL2014916 0.76 CYP19A1 (0.45) LMNAMAPTELANEATMTDP1
SCHEMBL11013322 0.75 LMNA (0.42) LMNASMN1; SMN2MAPTL3MBTL1KMT2A
SCHEMBL27145067 0.74 KDM4E (0.58) LMNAMAPTTDP1KMT2AMEN1
SCHEMBL689814 0.73 GAA (0.44) LMNASMN1; SMN2MAPTATML3MBTL1
SCHEMBL9355575 0.72 KMT2A (0.44) LMNAMAPTKMT2AMEN1RAB9A
SCHEMBL9358913 0.71 KMT2A (0.49) LMNASMN1; SMN2MAPTKMT2ARAB9A
SCHEMBL689834 0.71 KMT2A (0.43) LMNASMN1; SMN2MAPTELANETDP1
SCHEMBL28198215 0.71 MGLL (0.45) LMNASMN1; SMN2MAPTELANEL3MBTL1
SCHEMBL27720065 0.71 GRM4 (0.41) LMNASMN1; SMN2MAPTL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP claimed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US claimed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP claimed
EP-0242618-B1 Transparent optical article and process for preparing same NIPPON OILS & FATS CO LTD (JP) 1994-11-02 EP disclosed
US-4948854-A COPOLYMER INCLUDING ITACONIC ACID DIESTER SEIKO EPSON CORPORATION (JP) 1990-08-14 US disclosed
EP-0242618-A2 Transparent optical article and process for preparing same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-10-28 EP disclosed