Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627971 | 1.00 | MAOB (0.39) | MAOBDRD2DRD3MAPTADRA1D | |
| SCHEMBL9352243 | 0.93 | MAOB (0.37) | MAOBDRD2DRD3HRH3 | |
| SCHEMBL9351483 | 0.92 | MAOB (0.37) | MAOBDRD2DRD3 | |
| SCHEMBL9352195 | 0.91 | DRD2 (0.37) | MAOBDRD2DRD3ADRA1DADRA1A | |
| SCHEMBL9352179 | 0.91 | DRD2 (0.37) | MAOBDRD2DRD3ADRA1DADRA1A | |
| SCHEMBL9352116 | 0.91 | MEN1 (0.37) | MAOBDRD2DRD3 | |
| SCHEMBL9355275 | 0.89 | RAB9A (0.39) | MAPTHRH3 | |
| SCHEMBL9352225 | 0.89 | MAOA (0.36) | MAOBMAPTHRH3 | |
| SCHEMBL9355450 | 0.88 | LMNA (0.38) | — | |
| SCHEMBL9355068 | 0.88 | KMT2A (0.37) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410756-B1 | Cyclohexenylethane compounds | CHISSO CORP (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5064565-A | Liquid crystals | CHISSO CORPORATION (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0410756-A1 | Cyclohexenylethane compounds | Chisso Corporation (JP) | 1991-01-30 | — | — | EP | disclosed |
| US-4724097-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-02-09 | — | — | US | disclosed |
| EP-0125563-B1 | BICYCLOHEXYL ETHANES | MERCK PATENT GmbH (DE) | 1987-05-27 | — | — | EP | disclosed |
| US-4606845-A | DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-08-19 | — | — | US | disclosed |
| EP-0125563-A2 | Bicyclohexyl ethanes | MERCK PATENT GmbH (DE) | 1984-11-21 | — | — | EP | disclosed |