Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629728 | 0.89 | MTNR1A (0.44) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL25083791 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9AABCB11RXRARXRB | |
| SCHEMBL2227634 | 0.83 | TDP1 (0.46) | SMN1; SMN2RAB9APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1838537 | 0.83 | SIGMAR1 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL23046356 | 0.83 | SIGMAR1 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL9358146 | 0.83 | SIGMAR1 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL15890439 | 0.83 | PRKAB2 (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL9355102 | 0.82 | ALDH1A1 (0.51) | SMN1; SMN2RAB9AABCB11KMT2AMEN1 | |
| SCHEMBL29080969 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9AABCB11RXRARXRB | |
| SCHEMBL13657979 | 0.81 | KMT2A (0.42) | SMN1; SMN2RAB9ARXRARXRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |