Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402302 | 0.73 | MEN1 (0.40) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31558693 | 0.73 | MEN1 (0.40) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3253414 | 0.72 | MEN1 (0.42) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11197612 | 0.68 | MEN1 (0.54) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11792980 | 0.68 | SMN1; SMN2 (0.46) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1679789 | 0.66 | MAPT (0.43) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL28295668 | 0.66 | LMNA (0.41) | LMNAALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8947996 | 0.62 | SMN1; SMN2 (0.75) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31037175 | 0.61 | KMT2A (0.38) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL31037174 | 0.61 | KMT2A (0.38) | LMNAALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453927-B1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | UNIV DENMARK TECH DTU (DK) | 2019-05-15 | — | — | EP | disclosed |
| US-20150202336-A1 | Loading Technique for Preparing Radionuclide Containing Nanoparticles | RIGSHOSPITALET (DK) | 2015-07-23 | — | — | US | disclosed |
| US-8920775-B2 | Loading technique for preparing radionuclide containing nanoparticles | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2014-12-30 | — | — | US | disclosed |
| US-20120213698-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES | RIGSHOSPITALET (DK) | 2012-08-23 | — | — | US | disclosed |
| EP-2453927-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | Technical University of Denmark (DK) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006510-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202336-A1 | Loading Technique for Preparing Radionuclide Containing Nanoparticles | LIPG, NPC1L1, CD47 | LMNA 891/4885ALDH1A1 4468/4885KMT2A 3475/4885 |
| US-20120213698-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES | LIPG, NPC1L1, CD47 | LMNA 891/4885ALDH1A1 4468/4885KMT2A 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.