Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936005 | 0.81 | HTR4 (0.34) | ALDH1A1HPGDLIPEHTR4 | |
| SCHEMBL935161 | 0.78 | GNAI3 (0.43) | SMN1; SMN2 | |
| SCHEMBL10924227 | 0.74 | CTSL (0.36) | TSHRALDH1A1KMT2ALMNARAB9A | |
| SCHEMBL3703408 | 0.74 | TSHR (0.32) | TSHRALDH1A1KMT2AGAALMNA | |
| SCHEMBL12260412 | 0.73 | CYP2D6 (0.45) | TSHRALDH1A1NPSR1 | |
| SCHEMBL12283058 | 0.71 | USP2 (0.48) | TSHRALDH1A1KMT2AGAALMNA | |
| SCHEMBL658288 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28159570 | 0.69 | HTT (0.42) | TSHRALDH1A1KMT2AGAALMNA | |
| SCHEMBL2744386 | 0.67 | KDM1A (0.40) | TSHRALDH1A1KMT2AGAALMNA | |
| SCHEMBL6524170 | 0.67 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006808-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2011-01-20 | — | — | WO | disclosed |