SCHEMBL9356288

SCHEMBL9356288

NC(O)=S.OC(=S)N(c1ccccc1)c1ccccc1.[KH]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
L3MBTL1 Q9Y468 4/20 0.52
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
MAPT P10636 2/20 0.52
GAA P10253 1/20 0.52
HPGD P15428 1/20 0.52
NPSR1 Q6W5P4 2/20 0.46
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
FAAH O00519 1/20 0.39
PHGDH O43175 1/20 0.39
MGLL Q99685 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076535 0.98 ALDH1A1 (0.70) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL9356381 0.95 ALDH1A1 (0.67) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL3767158 0.95 ALDH1A1 (0.67) ALDH1A1L3MBTL1KMT2AMEN1MAPT
Methane SCHEMBL11116286 0.93 ALDH1A1 (0.64) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL3068207 0.90 ALDH1A1 (0.64) ALDH1A1L3MBTL1KMT2AMEN1MAPT
Hydrochloric Acid SCHEMBL11246737 0.87 ALDH1A1 (0.61) ALDH1A1L3MBTL1KMT2AMEN1MAPT
Benzenesulfonamide SCHEMBL11568847 0.81 CA2 (0.55) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL81706 0.80 ALDH1A1 (1.00) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL28245419 0.79 ALDH1A1 (0.64) ALDH1A1L3MBTL1KMT2AMEN1MAPT
SCHEMBL28457286 0.78 ALDH1A1 (0.95) ALDH1A1L3MBTL1KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2860170-B1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE OSAKA ORGANIC CHEMICAL IND LTD (JP) 2019-08-28 EP disclosed
US-9670129-B2 Process for preparing 4-hydroxybutyl acrylate OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-06-06 US disclosed
US-20150126766-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2015-05-07 US disclosed
EP-2860170-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE Osaka Organic Chemical Ind., Ltd. (JP) 2015-04-15 EP disclosed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed
US-4870156-A Removal of catalyst residues from olefin/carbon monoxide polymer with dithiocarbamate SHELL OIL COMPANY (US) 1989-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126766-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE LTB4R2, LTA4H, LTB4R ALDH1A1 261/4885L3MBTL1 3475/4885KMT2A 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.