Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574184 | 0.90 | ELANE (0.51) | ELANEKDM1ACA2OGAMAPKAPK2 | |
| SCHEMBL8387548 | 0.89 | ELANE (0.64) | ELANEKDM1ACA2OGAMAPKAPK2 | |
| SCHEMBL9442127 | 0.87 | ELANE (0.38) | ELANEKDM1ACA2 | |
| SCHEMBL9619081 | 0.82 | MAPT (0.37) | ELANEPOLBMAPTPKMMEN1 | |
| SCHEMBL9442120 | 0.79 | PKM (0.39) | ELANECA2POLBMAPTPKM | |
| SCHEMBL9355880 | 0.79 | MMP2 (0.32) | ELANE | |
| SCHEMBL8323108 | 0.78 | ELANE (0.66) | ELANEKDM1ACA2OGAMAPKAPK2 | |
| SCHEMBL8319671 | 0.78 | ELANE (0.57) | ELANEKDM1ACA2MAPKAPK2POLB | |
| SCHEMBL4061370 | 0.78 | ELANE (0.81) | ELANEKDM1ACA2MAPKAPK2MAPT | |
| SCHEMBL9356273 | 0.77 | ELANE (0.42) | ELANEMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401696-B1 | Process for production of sulfonium compounds and novel methylthiophenyl derivatives | MITSUBISHI GAS CHEMICAL CO (JP) | 1994-09-14 | — | — | EP | disclosed |
| US-5187311-A | Intermediates for sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0346756-B1 | PROCESS FOR PRODUCTION OF SULFONIUM COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-10-28 | — | — | EP | disclosed |
| US-5075476-A | Reacting alkylthiophenyl carbonates with dialkyl sulfates in presence of carbonates, bicarbonates, oxides or hydroxides of group I or II metals | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-5021197-A | Reacting a p-dialkylsulfoniophenol with a carbonyl halogenide in the presence of a secondary amine | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0401696-A2 | Process for production of sulfonium compounds and novel methylthiophenyl derivatives | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1990-12-12 | — | — | EP | disclosed |
| EP-0346756-A1 | Process for production of sulfonium compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1989-12-20 | — | — | EP | disclosed |