Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357454 | 0.89 | CES2 (0.45) | HPGDCYP3A4POLBMAPTSMN1; SMN2 | |
| SCHEMBL9356846 | 0.89 | HPGD (0.45) | HPGDTDP1ABCB1HSD17B1HSD17B2 | |
| SCHEMBL9357446 | 0.89 | THRB (0.42) | HPGDABCB1PARP1CYP2C19POLB | |
| SCHEMBL9357027 | 0.89 | KMT2A (0.40) | HPGDTDP1PARP1CYP2C19CYP3A4 | |
| SCHEMBL9357063 | 0.88 | ABCB1 (0.40) | ABCB1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL9854889 | 0.88 | KCNK3 (0.45) | HPGDTDP1ABCB1PARP1CYP2C19 | |
| SCHEMBL9360809 | 0.87 | ABCB1 (0.46) | HPGDTDP1ABCB1HSD17B1HSD17B2 | |
| SCHEMBL9357284 | 0.87 | BCL2 (0.38) | HPGDTDP1ABCB1HSD17B1HSD17B2 | |
| SCHEMBL9356941 | 0.83 | HPGD (0.40) | HPGDTDP1ABCB1PARP1POLB | |
| SCHEMBL9356770 | 0.82 | CNR1 (0.38) | CYP2C19CYP3A4CYP2C9TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-B1 | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1994-12-07 | — | — | EP | claimed |
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | claimed |