Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357446 | 0.92 | THRB (0.42) | KCNK3KCNK9RXFP1THRBHPGD | |
| SCHEMBL9357012 | 0.88 | HPGD (0.43) | KCNK3HPGDTDP1ABCB1CYP2C19 | |
| SCHEMBL9357142 | 0.84 | LMNA (0.41) | KCNK3KCNK9HPGDTDP1ABCB1 | |
| SCHEMBL9356794 | 0.84 | ABCB1 (0.42) | KCNK3KCNK9RXFP1THRBHPGD | |
| SCHEMBL9356888 | 0.84 | KCNK3 (0.41) | KCNK3KCNK9HPGDTDP1ABCB1 | |
| SCHEMBL9357277 | 0.84 | ABCB1 (0.47) | RXFP1THRBHPGDABCB1ALDH1A1 | |
| SCHEMBL9356789 | 0.84 | HPGD (0.39) | KCNK3KCNK9RXFP1THRBHPGD | |
| SCHEMBL9356846 | 0.82 | HPGD (0.45) | HPGDTDP1ABCB1CYP2C19SMN1; SMN2 | |
| SCHEMBL9357123 | 0.82 | ABCB1 (0.47) | RXFP1THRBHPGDABCB1ALDH1A1 | |
| SCHEMBL9357094 | 0.82 | ABCB1 (0.40) | RXFP1THRBHPGDABCB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461809-A1 | Dibenzoylalkylcyanohydrazines | ROHM AND HAAS COMPANY (US) | 1991-12-18 | — | — | EP | claimed |