Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358203 | 1.00 | RXRA (0.54) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9680935 | 0.95 | RXRA (0.53) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9680956 | 0.93 | RXRA (0.48) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8984878 | 0.93 | PPARG (0.49) | RXRAPPARGPPARACNR2SMPD1 | |
| SCHEMBL9680898 | 0.88 | MAPT (0.47) | RXRACYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL9681186 | 0.88 | CNR1 (0.44) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL8984886 | 0.87 | MAPT (0.49) | CYP1A2CYP3A4CYP2C19PPARGPPARA | |
| SCHEMBL9362344 | 0.85 | HDAC1 (0.43) | RXRACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9357859 | 0.85 | RXRA (0.72) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9358171 | 0.85 | RXRA (0.72) | RXRACYP1A2CYP3A4CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-B1 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI CHEMICAL IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |