Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680956 | 0.91 | RXRA (0.48) | MAPTRXRAALOX5OR51E2MTNR1A | |
| SCHEMBL9680935 | 0.91 | RXRA (0.53) | MAPTRXRAALOX5CYP1A2CYP3A4 | |
| SCHEMBL9358203 | 0.88 | RXRA (0.54) | RXRACYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL9358192 | 0.88 | RXRA (0.54) | RXRACYP1A2CYP3A4CYP2C19CNR1 | |
| SCHEMBL9681186 | 0.88 | CNR1 (0.44) | MAPTRXRAALOX5OR51E2MTNR1A | |
| SCHEMBL9362344 | 0.87 | HDAC1 (0.43) | MAPTRXRAALOX5OR51E2MTNR1A | |
| SCHEMBL9362113 | 0.86 | GABRA1 (0.53) | ALOX5OR51E2MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL8984897 | 0.86 | CNR1 (0.51) | ALOX5OR51E2MTNR1AMTNR1BCNR1 | |
| SCHEMBL8984886 | 0.84 | MAPT (0.49) | MAPTMTNR1AMTNR1BCYP1A2CYP3A4 | |
| SCHEMBL8984878 | 0.83 | PPARG (0.49) | MAPTRXRACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |