Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984875 | 0.94 | MAPT (0.45) | GABRA1GABRB2MAPTCYP3A4CYP2C9 | |
| SCHEMBL9680935 | 0.90 | RXRA (0.53) | CNR1CNR2RXRAALOX5GABRA1 | |
| SCHEMBL9680956 | 0.90 | RXRA (0.48) | CNR1CNR2RXRAALOX5OR51E2 | |
| SCHEMBL9362113 | 0.88 | GABRA1 (0.53) | ALOX5OR51E2MTNR1AMTNR1BGABRA1 | |
| SCHEMBL9358192 | 0.88 | RXRA (0.54) | CNR1CNR2RXRACYP1A2CYP3A4 | |
| SCHEMBL9358203 | 0.88 | RXRA (0.54) | CNR1CNR2RXRACYP1A2CYP3A4 | |
| SCHEMBL8984897 | 0.88 | CNR1 (0.51) | CNR1CNR2ALOX5OR51E2MTNR1A | |
| SCHEMBL9680898 | 0.88 | MAPT (0.47) | CNR1CNR2RXRAALOX5OR51E2 | |
| SCHEMBL9362344 | 0.85 | HDAC1 (0.43) | RXRAALOX5OR51E2MTNR1AMTNR1B | |
| SCHEMBL8984886 | 0.83 | MAPT (0.49) | MTNR1AMTNR1BMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |