Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.57 |
| ▸ | FEN1 | P39748 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9358909 | 0.79 | ERCC5 (0.54) | ERCC5FEN1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8154620 | 0.79 | ERCC5 (0.74) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL9355491 | 0.74 | ALDH1A1 (0.46) | ERCC5FEN1ALDH1A1RECQLHPGD | |
| SCHEMBL1697496 | 0.72 | TSHR (0.69) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11419345 | 0.72 | ALDH1A1 (0.77) | SMN1; SMN2TSHRCASP1KDM4EMAPT | |
| SCHEMBL111279 | 0.72 | TSHR (1.00) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL11380224 | 0.71 | POLB (0.64) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL481408 | 0.70 | ALDH1A1 (0.65) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| Thioglycolic Acid SCHEMBL8860110 | 0.70 | SMN1; SMN2 (0.78) | ERCC5FEN1SMN1; SMN2TSHRCASP1 | |
| SCHEMBL6233608 | 0.70 | TSHR (0.95) | ERCC5FEN1SMN1; SMN2TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | claimed |