SCHEMBL9358683

SCHEMBL9358683

CCOC(=O)CNC(c1ccc(N(C)C)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.45
GAA P10253 6/20 0.44
ALDH1A1 P00352 10/20 0.44
ADORA3 P0DMS8 1/20 0.43
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
MAPT P10636 6/20 0.42
NPC1 O15118 4/20 0.42
RAB9A P51151 3/20 0.42
PSMD14 O00487 1/20 0.41
MAPK1 P28482 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
MCL1 Q07820 1/20 0.40
POLB P06746 1/20 0.39
ALPG P10696 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7446250 0.81 NPSR1 (0.60) NPSR1ALDH1A1ADORA3MEN1KMT2A
Methylene Chloride SCHEMBL28217271 0.78 NPSR1 (0.57) NPSR1ALDH1A1ADORA3MEN1KMT2A
SCHEMBL3835577 0.77 MEN1 (0.55) NPSR1ADORA3MEN1KMT2ATDP1
SCHEMBL21199743 0.76 GAA (0.47) NPSR1GAAALDH1A1MEN1KMT2A
SCHEMBL28858391 0.73 ADORA3 (0.56) NPSR1ALDH1A1ADORA3MEN1KMT2A
SCHEMBL1578840 0.73 GAA (0.54) NPSR1GAAALDH1A1MEN1KMT2A
SCHEMBL5094824 0.72 ALDH1A1 (0.52) GAAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL28514782 0.72 NPSR1 (0.54) NPSR1ALDH1A1ADORA3MEN1KMT2A
SCHEMBL512626 0.71 CYP4Z1 (0.55) GAAALDH1A1MEN1KMT2AL3MBTL1
SCHEMBL1578781 0.71 GAA (0.48) NPSR1GAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390432-B1 Color-former JUJO PAPER CO LTD (JP) 1994-10-19 EP disclosed
US-5178949-A Microcapsule with colorless dye, hydrophobic solvent, oil soluble nonionic surfactant JUJO PAPER CO., LTD. (JP) 1993-01-12 US disclosed
EP-0390432-A2 Color-former NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1990-10-03 EP disclosed
EP-0196484-B1 PRESSURE SENSITIVE MANIFOLD SHEET KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1990-05-09 EP disclosed
US-4704379-A Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-11-03 US disclosed
EP-0196484-A1 Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-10-08 EP disclosed
US-4349454-A ENCAPSULATION OF A HYDROPHOBIC-SOLVENT SOLUTION OF A DIAMINODIARYL METHANE SULFONE DERIVATIVE KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-09-14 US disclosed