Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16971053 | 0.85 | ALDH1A1 (0.50) | L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9551017 | 0.85 | KMT2A (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL28713222 | 0.84 | KMT2A (0.47) | L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9358824 | 0.83 | SLC22A12 (0.48) | L3MBTL1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3024537 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3024541 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL3024539 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30737471 | 0.80 | L3MBTL1 (0.68) | L3MBTL1KMT2AMEN1ERN1ALDH1A1 | |
| SCHEMBL719391 | 0.80 | L3MBTL1 (0.68) | L3MBTL1KMT2AMEN1ERN1ALDH1A1 | |
| SCHEMBL129889 | 0.79 | ALDH1A1 (0.69) | L3MBTL1KMT2AMEN1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489836-B1 | LIGHT ACTIVATED ACYL-ENZYMES | UNIV DUKE (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5218137-A | Chemical light amplifiers | DUKE UNIVERSITY (US) | 1993-06-08 | — | — | US | disclosed |
| US-5114851-A | Serine- or cysteine-containing protease modified by nucleophilic cinnamic acid; photoisomerization; biological switches; medical diagnosis | DUKE UNIVERSITY (US) | 1992-05-19 | — | — | US | disclosed |