Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7821293 | 0.78 | TDP1 (0.44) | MAPTKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7832200 | 0.74 | GPR35 (0.50) | MAPTPOLBGPR35KMT2ASMN1; SMN2 | |
| SCHEMBL30991375 | 0.71 | MAPT (0.50) | MAPTPOLBAPEX1CASP6CSNK2A2 | |
| SCHEMBL7828554 | 0.70 | TDP1 (0.50) | KMT2ASMN1; SMN2ALDH1A1MEN1S100A4 | |
| SCHEMBL5707256 | 0.70 | ALDH1A1 (0.59) | MAPTPOLBAPEX1CASP6CSNK2A2 | |
| SCHEMBL1173852 | 0.70 | TDP1 (0.54) | MAPTPOLBGPR35KMT2ASMN1; SMN2 | |
| SCHEMBL8944624 | 0.70 | MAPT (0.53) | MAPTPOLBAPEX1CASP6CSNK2A2 | |
| SCHEMBL3476440 | 0.69 | MAPT (0.59) | MAPTPOLBAPEX1CASP6CSNK2A2 | |
| SCHEMBL27993054 | 0.69 | CASP6 (0.51) | MAPTPOLBAPEX1CASP6CSNK2A2 | |
| SCHEMBL2289877 | 0.69 | TSHR (0.50) | MAPTGPR35KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489836-B1 | LIGHT ACTIVATED ACYL-ENZYMES | UNIV DUKE (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5218137-A | Chemical light amplifiers | DUKE UNIVERSITY (US) | 1993-06-08 | — | — | US | disclosed |