SCHEMBL9358985

SCHEMBL9358985

CN([SiH](C)C)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
KCNN4 O15554 1/20 0.31
FAAH O00519 1/20 0.30
PHGDH O43175 1/20 0.30
MGLL Q99685 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1526078 0.79 ESR1 (0.35) ESR1ESR2ALDH1A1TSHRKCNN4
SCHEMBL328747 0.79 ESR1 (0.35) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL3069583 0.74 ESR1 (0.37) OPRM1OPRK1OPRL1ESR1ESR2
SCHEMBL2276954 0.74 ESR1 (0.37) OPRM1OPRK1OPRL1ESR1ESR2
SCHEMBL328759 0.73 NPSR1 (0.33) ESR1ESR2MEN1KMT2AFAAH
SCHEMBL4949411 0.70
Toluene SCHEMBL28224989 0.68 TSHR (0.48) ALDH1A1TSHRCA12CA9
SCHEMBL11543775 0.67 TSHR (0.36) OPRM1ESR1ESR2ALDH1A1TSHR
SCHEMBL6473845 0.66
SCHEMBL28949883 0.66 ALDH1A1 (0.40) KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310320-B1 Curable composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-12-28 EP claimed
US-4923948-A Curable composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-08 US claimed
EP-0310320-A2 Curable composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-04-05 EP claimed
EP-0310320-B1 Curable composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-12-28 EP disclosed
US-4923948-A Curable composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-08 US disclosed
EP-0310320-A2 Curable composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-04-05 EP disclosed
US-4732994-A POWER TRANSMISSION FLUIDS WACKER-CHEMIE GMBH (DE) 1988-03-22 US disclosed
EP-0249960-A2 Stabilized organopolysiloxane oils Wacker-Chemie GmbH (DE) 1987-12-23 EP disclosed