Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086185 | 0.88 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL159766 | 0.81 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL8610607 | 0.81 | LMNA (0.38) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL29351145 | 0.81 | LMNA (0.38) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL321113 | 0.81 | LMNA (0.38) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL8931556 | 0.81 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL22415048 | 0.80 | ALDH1A1 (0.35) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL23235917 | 0.79 | LMNA (0.39) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL23859813 | 0.79 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 | |
| SCHEMBL11367709 | 0.79 | LMNA (0.39) | LMNASMN1; SMN2HSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224590-B1 | METHOD FOR ASSAYING HUMAN PULMONARY SURFACE ACTIVE SUBSTANCE AND REAGENT KIT THEREFOR | TEIJIN LTD (JP) | 1994-11-23 | — | — | EP | disclosed |