Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610607 | 0.87 | LMNA (0.38) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29351145 | 0.87 | LMNA (0.38) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL321113 | 0.87 | LMNA (0.38) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22415048 | 0.83 | ALDH1A1 (0.35) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18889869 | 0.83 | LMNA (0.33) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL28514925 | 0.83 | LMNA (0.45) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3696095 | 0.82 | LMNA (0.41) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23859815 | 0.82 | KMT2A (0.34) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL20384698 | 0.80 | LMNA (0.37) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23235917 | 0.80 | LMNA (0.39) | LMNARAB9AALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031999-A2 | Antitumor protein hybrid and process for the preparation thereof | TEIJIN LIMITED (JP) | 1981-07-15 | — | — | EP | disclosed |