Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146819 | 0.98 | ABL1 (0.51) | ALOX15ABL1KCNH3CNR2NR4A2 | |
| SCHEMBL31146773 | 0.98 | ABL1 (0.51) | ALOX15ABL1KCNH3CNR2NR4A2 | |
| SCHEMBL18893409 | 0.88 | KMT2A (0.41) | ALOX15CISD1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9359772 | 0.83 | KCNH3 (0.45) | ABL1KCNH3CNR2CNR1ACHE | |
| SCHEMBL16224813 | 0.81 | SOAT1 (0.45) | ABL1KCNH3CNR2CNR1ACHE | |
| SCHEMBL9400095 | 0.81 | ABL1 (0.50) | ABL1CNR2NR4A2CISD1HCAR3 | |
| SCHEMBL12471164 | 0.80 | KMT2A (0.43) | ALOX15KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9363853 | 0.77 | PKM (0.43) | KCNH3HCAR3 | |
| SCHEMBL18208607 | 0.77 | KMT2A (0.44) | ALOX15KMT2A | |
| SCHEMBL11315849 | 0.76 | TLR8 (0.46) | ALOX15ABL1NR4A2CISD1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117084-A1 | NOVEL ISOQUINOLINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-10-14 | — | — | WO | disclosed |