Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716629 | 0.86 | MAPT (0.63) | MAOBMAPTNPC1RAB9APOLB | |
| SCHEMBL29436304 | 0.80 | MAOB (0.54) | MAOBMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7865335 | 0.80 | MAOB (0.54) | MAOBMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL21671652 | 0.79 | NPC1 (0.49) | MAPTNPC1RAB9APOLBCYP2C9 | |
| SCHEMBL9161768 | 0.79 | LTA4H (0.46) | MAPTNPC1RAB9APOLBCYP2C9 | |
| SCHEMBL309289 | 0.78 | MAOB (0.63) | MAOBMAPTNPC1RAB9APOLB | |
| SCHEMBL31563609 | 0.78 | MAOB (0.63) | MAOBMAPTNPC1RAB9APOLB | |
| SCHEMBL29363383 | 0.78 | MAOB (0.63) | MAOBMAPTNPC1RAB9APOLB | |
| SCHEMBL15474288 | 0.78 | MAOB (0.63) | MAOBMAPTNPC1RAB9APOLB | |
| SCHEMBL7858687 | 0.78 | MAOB (0.63) | MAOBMAPTNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192480-B1 | Bis(3-aminophenoxy) aromatics and method of preparing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-11-23 | — | — | EP | disclosed |
| US-5077436-A | Reacting dihydroxy derivatives with m-dinitrobenzene; reducing | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0192480-A1 | Bis(3-aminophenoxy) aromatics and method of preparing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-08-27 | — | — | EP | disclosed |