Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9709290 | 0.91 | SMN1; SMN2 (0.53) | PRSS1ACRSMN1; SMN2HPGDXBP1 | |
| SCHEMBL2221244 | 0.82 | PARP10 (0.46) | PRSS1SMN1; SMN2HPGDMAPTKDM4E | |
| SCHEMBL9360544 | 0.80 | MAPT (0.51) | SMN1; SMN2HPGDMAPTMEN1KMT2A | |
| SCHEMBL9360679 | 0.80 | LMNA (0.53) | PRSS1ACRSMN1; SMN2HPGDMAPT | |
| SCHEMBL1485799 | 0.80 | PARP10 (0.52) | PRSS1ACRSMN1; SMN2MAPTMAPK1 | |
| SCHEMBL2729152 | 0.80 | PRSS1 (0.55) | PRSS1ACRSMN1; SMN2HPGDXBP1 | |
| SCHEMBL29062391 | 0.78 | SMN1; SMN2 (0.51) | PRSS1ACRSMN1; SMN2HPGDXBP1 | |
| SCHEMBL7459980 | 0.78 | PARP10 (0.46) | XBP1MAPTKDM4ERAB9AMEN1 | |
| SCHEMBL4596363 | 0.77 | THRB (0.54) | PRSS1ACRSMN1; SMN2HPGDXBP1 | |
| SCHEMBL9360644 | 0.76 | POLB (0.55) | SMN1; SMN2HPGDMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |