Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 5/20 | 0.61 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986259 | 0.85 | MEN1 (0.59) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL20827920 | 0.83 | MEN1 (0.49) | SHMT1SHMT2MEN1KMT2AHDAC8 | |
| SCHEMBL20241470 | 0.82 | SHMT1 (0.62) | SHMT1SHMT2 | |
| SCHEMBL11196739 | 0.81 | MEN1 (0.55) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL25144167 | 0.80 | HPGD (0.56) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL6188972 | 0.80 | HPGD (0.56) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL9360320 | 0.80 | P2RX7 (0.55) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL10982724 | 0.80 | HPGD (0.75) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL15086400 | 0.79 | MEN1 (0.52) | MEN1KMT2AHDAC8HDAC6HPGD | |
| SCHEMBL31117181 | 0.79 | POLB (0.60) | MEN1KMT2AHDAC8HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |