Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357314 | 0.89 | PTGES (0.46) | PPARGPPARAALOX5MMEACE | |
| SCHEMBL9360756 | 0.84 | TDP1 (0.48) | SMN1; SMN2 | |
| SCHEMBL9361003 | 0.82 | NPY5R (0.43) | NPY5RNR3C1SRD5A2PPARGPPARA | |
| SCHEMBL9356743 | 0.79 | PPARG (0.45) | PPARGPPARA | |
| SCHEMBL28970987 | 0.75 | ALDH1A1 (0.66) | SMN1; SMN2 | |
| SCHEMBL9360958 | 0.75 | CTBP2 (0.42) | PPARGPPARASMN1; SMN2FFAR1 | |
| SCHEMBL9360750 | 0.74 | TDP1 (0.49) | SMN1; SMN2 | |
| SCHEMBL10048247 | 0.74 | SMN1; SMN2 (0.66) | NPY5RNR3C1SRD5A2EPHX2ALOX5 | |
| SCHEMBL20166110 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2 | |
| SCHEMBL2327420 | 0.74 | CTRB1 (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-B1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1994-12-07 | — | — | EP | disclosed |
| EP-0415185-A1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |