Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559961 | 0.82 | MAOA (0.51) | ALDH1A1ALOX15MAOAMAOBCDK1 | |
| SCHEMBL9480031 | 0.82 | MAOA (0.51) | ALDH1A1ALOX15MAOAMAOBCDK1 | |
| SCHEMBL1881521 | 0.79 | LPL (0.53) | — | |
| SCHEMBL7536683 | 0.79 | LPL (0.53) | — | |
| SCHEMBL3025911 | 0.79 | MAOA (0.45) | ALDH1A1MAOAMAOBCDK1UNG | |
| SCHEMBL4083034 | 0.79 | LPL (0.53) | — | |
| SCHEMBL11440647 | 0.79 | LPL (0.53) | — | |
| SCHEMBL5147572 | 0.79 | LPL (0.53) | — | |
| SCHEMBL22098517 | 0.79 | MAOA (0.41) | ALDH1A1MAOAMAOBCDK1UNG | |
| SCHEMBL20233485 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAOAMAOBCDK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403250-B1 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0403250-A2 | Phenylglycidamides useful for preparing alpha-hydroxy-beta-sulfido-arylpropionic acid derivatives | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |