Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360783 | 0.91 | ADRA2A (0.37) | ALDH1A1SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL10476510 | 0.82 | LMNA (0.36) | LMNAEGLN1ALKBH5SUCNR1PHF8 | |
| SCHEMBL10011936 | 0.81 | LMNA (0.35) | LMNAEGLN1ALKBH5SUCNR1PHF8 | |
| SCHEMBL10010776 | 0.80 | GSTP1 (0.46) | ALDH1A1TSHRADRA2AADRA1AMAPT | |
| SCHEMBL3097747 | 0.79 | LDHA (0.36) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14063623 | 0.79 | DGKA (0.45) | LMNAALDH1A1TSHRPAMMAPT | |
| SCHEMBL10010683 | 0.78 | LMNA (0.39) | LMNAEGLN1ALKBH5SUCNR1PHF8 | |
| SCHEMBL10476525 | 0.78 | PTPN7 (0.40) | LMNAALDH1A1MAPTBLM | |
| SCHEMBL10476518 | 0.78 | PTPN7 (0.36) | LMNAEGLN1PHF8KDM2AKDM6B | |
| SCHEMBL6339036 | 0.77 | LMNA (0.41) | LMNAEGLN1ALKBH5SUCNR1PHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214853-B1 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING & MFG (US) | 1994-11-30 | — | — | EP | disclosed |
| US-4883864-A | COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851513-A | Viscoelastic collagen solution for opthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4713446-A | COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0214853-A2 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |