Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360756 | 0.85 | TDP1 (0.48) | TDP1POLBAPEX1MEN1KMT2A | |
| SCHEMBL9357294 | 0.84 | TSHR (0.42) | TRPM8TDP1MEN1KMT2ATSHR | |
| SCHEMBL9357000 | 0.83 | ALDH1A1 (0.42) | TRPM8POLBMEN1KMT2ATSHR | |
| SCHEMBL9360750 | 0.80 | TDP1 (0.49) | TDP1POLBAPEX1MEN1KMT2A | |
| SCHEMBL9357323 | 0.80 | OPRK1 (0.46) | TRPM8POLBMEN1KMT2ACYP3A4 | |
| SCHEMBL9357340 | 0.78 | CTBP2 (0.38) | CYP3A4CYP2D6CYP2C9CYP2C19KDM4E | |
| SCHEMBL6136604 | 0.77 | LMNA (0.41) | TRPM8TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL9357319 | 0.75 | TDP1 (0.41) | TDP1POLBAPEX1MEN1KMT2A | |
| SCHEMBL9361003 | 0.73 | NPY5R (0.43) | MEN1KMT2ACCR5CNR2 | |
| SCHEMBL9483734 | 0.72 | TRPM8 (0.54) | TRPM8TDP1POLBAPEX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415185-B1 | 4-Alkoxy- and 4-(substituted)amino-3-arylpyrrolinones derivatives | BAYER AG (DE) | 1994-12-07 | — | — | EP | disclosed |