Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360806 | 0.81 | ADRB2 (0.53) | SMN1; SMN2ADRB3ADRB2ADRB1ADRA1D | |
| SCHEMBL31603899 | 0.78 | CTSV (0.51) | CTSVCTSLPDCD1CD274POLB | |
| SCHEMBL718147 | 0.71 | CTSV (0.52) | SMN1; SMN2CTSVCTSLPDCD1CD274 | |
| SCHEMBL4594348 | 0.71 | CTSV (0.52) | CTSVCTSLPOLBADRA1DADRA1A | |
| SCHEMBL2671920 | 0.71 | CTSV (0.52) | SMN1; SMN2CTSVCTSLPDCD1CD274 | |
| SCHEMBL29897031 | 0.71 | CTSV (0.52) | SMN1; SMN2CTSVCTSLPDCD1CD274 | |
| SCHEMBL718146 | 0.71 | CTSV (0.52) | SMN1; SMN2CTSVCTSLPDCD1CD274 | |
| SCHEMBL5099246 | 0.71 | CTSV (0.52) | CTSVCTSLPOLBADRA1DADRA1A | |
| SCHEMBL29896946 | 0.71 | CTSV (0.52) | SMN1; SMN2CTSVCTSLPDCD1CD274 | |
| SCHEMBL10554925 | 0.71 | CTSV (0.54) | NPC1RAB9ASMN1; SMN2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |