Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328727 | 0.83 | RAB9A (0.60) | FPR2RAB9APOLBKMT2AMEN1 | |
| SCHEMBL23329075 | 0.80 | SAE1 (0.50) | KDM4EFPR2L3MBTL1NPC1POLB | |
| SCHEMBL25840768 | 0.80 | NPC1 (0.60) | FPR2ALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL23328367 | 0.80 | ACP1 (0.59) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14559568 | 0.78 | SMN1; SMN2 (0.55) | KDM4EALDH1A1L3MBTL1RAB9ANPC1 | |
| SCHEMBL9365783 | 0.77 | FPR2 (0.46) | KDM4EFPR2ALDH1A1NPC1KMT2A | |
| SCHEMBL23328674 | 0.76 | HDAC3 (0.58) | KDM4EFPR2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL8214915 | 0.76 | SAE1 (0.58) | KDM4EALDH1A1RAB9AMAPK1POLB | |
| SCHEMBL23328365 | 0.76 | FPR2 (0.67) | FPR2KMT2AMEN1MAPTCA12 | |
| SCHEMBL23328366 | 0.76 | RAB9A (0.64) | KDM4EFPR2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417256-B1 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS | NUTRASWEET CO (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5266717-A | Suppressors of sweet and/or bitter tastes, adjuvants for foods or drugs | NUTRASWEET PROPERTY HOLDINGS, INC. | 1993-11-30 | — | — | US | disclosed |
| EP-0417256-A4 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS | — | 1991-09-25 | — | — | EP | disclosed |
| EP-0417256-A1 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS. | NUTRASWEET CO (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994490-A | To inhibit or lessen sweet or bitter tastes in foods, beverage or drugs | THE NUTRASWEET COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| WO-1990011695-A1 | NOVEL N-(SULFOMETHYL)-N'-ARYLUREAS | THE NUTRASWEET COMPANY (US) | 1990-10-18 | — | — | WO | disclosed |