Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.58 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 4/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23329073 | 0.83 | CA2 (0.53) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL25840768 | 0.82 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1CA12CA1 | |
| SCHEMBL20708118 | 0.81 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL9435964 | 0.80 | RAB9A (0.72) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL11092496 | 0.79 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL23328727 | 0.79 | RAB9A (0.60) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL23329075 | 0.79 | SAE1 (0.50) | NPC1SAE1UBA2CA12CA1 | |
| SCHEMBL4588526 | 0.79 | RAB9A (0.70) | RAB9ASMN1; SMN2NPC1SAE1UBA2 | |
| SCHEMBL8688090 | 0.78 | GAA (0.57) | RAB9ASMN1; SMN2NPC1CA12CA1 | |
| SCHEMBL23328367 | 0.78 | ACP1 (0.59) | RAB9ASMN1; SMN2NPC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | Kent Innovation & Enterprise (GB) | 2023-07-18 | — | — | US | disclosed |
| US-20210128501-A1 | ANTIBACTERIAL COMPOUNDS | KENT INNOVATION & ENTERPRISE, UNIVERSITY OF KENT (GB) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | ARF1, ARL1, TLR1 | RAB9A 1656/4885SMN1; SMN2 3087/4885NPC1 407/4885 |
| US-20210128501-A1 | ANTIBACTERIAL COMPOUNDS | ARF1, ARL1, TLR1 | RAB9A 1656/4885SMN1; SMN2 3087/4885NPC1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.