Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 4/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893032 | 0.85 | CYP1A2 (0.48) | CYP2D6SUMO2SUMO1SENP7SENP2 | |
| SCHEMBL11829843 | 0.79 | SUMO2 (0.53) | CYP2D6POLBSUMO2SUMO1SENP7 | |
| SCHEMBL11433519 | 0.77 | CYP2D6 (0.51) | CYP2D6POLBSENP7CTRB1MAPT | |
| SCHEMBL10488063 | 0.76 | CYP2D6 (0.38) | CYP2D6CTRB1MPLCTRCEP300 | |
| SCHEMBL8701010 | 0.75 | THRB (0.49) | CYP2D6SENP7MAPTTDP1KMT2A | |
| SCHEMBL8701015 | 0.75 | THRB (0.49) | CYP2D6SENP7MAPTTDP1KMT2A | |
| SCHEMBL11015138 | 0.74 | CYP2D6 (0.51) | CYP2D6POLBCTRB1MPLCTRC | |
| SCHEMBL8101961 | 0.74 | CYP2D6 (0.52) | CYP2D6MAPTTDP1KMT2AMEN1 | |
| SCHEMBL11781199 | 0.73 | CASP6 (0.53) | CYP2D6POLBPRMT3EP300PRMT6 | |
| SCHEMBL2856243 | 0.73 | CYP2D6 (0.57) | CYP2D6POLBSUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5021559-A | Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0399411-A1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-28 | — | — | EP | disclosed |
| US-4564672-A | Water-soluble monoazo and disazo compounds containing a fibre-reactive 2-alkoxy-5-chloro-aniline diazo component and copper complexes thereof, useful as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-14 | — | — | US | disclosed |
| US-4218373-A | FOR DYEING WOOL AND POLYAMIDES, DEEP RED TO VIOLET | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |