Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701015 | 1.00 | THRB (0.49) | THRBTDP1CYP1A1TSHRCYP1B1 | |
| Hydrochloric Acid SCHEMBL5846986 | 0.81 | TSHR (0.50) | THRBTDP1CYP1A1TSHRCYP1B1 | |
| SCHEMBL1572609 | 0.80 | TSHR (0.52) | THRBTDP1CYP1A1TSHRCYP1B1 | |
| SCHEMBL1348095 | 0.80 | TSHR (0.52) | THRBTDP1CYP1A1TSHRCYP1B1 | |
| SCHEMBL29176235 | 0.78 | CDC25B (0.49) | THRBTDP1KMT2AMEN1NPC1 | |
| SCHEMBL29093547 | 0.76 | PTPN22 (0.48) | TDP1TSHRKMT2AMEN1NPC1 | |
| SCHEMBL9363554 | 0.75 | CYP2D6 (0.46) | THRBTDP1CYP1A1TSHRCYP1B1 | |
| SCHEMBL20152833 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1NPC1L3MBTL1RAB9A | |
| Phenol SCHEMBL30182897 | 0.74 | LDHA (0.45) | THRBTDP1KMT2AMEN1L3MBTL1 | |
| SCHEMBL564010 | 0.73 | KMT2A (0.78) | THRBTDP1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5779739-A | Dye mixtures of fiber-reactive azo dyes and their use for dyeing hydroxy-and/or carboxamido-containing fiber material | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-14 | — | — | US | disclosed |
| EP-0399411-A1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0381133-A1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |