Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007546 | 0.85 | HSP90AA1 (0.39) | ARTP53PIM1PIM2HSP90AA1 | |
| SCHEMBL936383 | 0.80 | GABRA1 (0.42) | ARMETAP2PIM1PIM2KDR | |
| SCHEMBL13399048 | 0.79 | ALDH1A1 (0.48) | GAAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL1005516 | 0.76 | PTGS2 (0.33) | HSP90AA1 | |
| SCHEMBL13542409 | 0.76 | KDM4E (0.43) | GAAMETAP2ALDH1A1HPGDALOX15 | |
| SCHEMBL989648 | 0.73 | AR (0.46) | ARGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL1005514 | 0.72 | — | — | |
| SCHEMBL7772549 | 0.72 | ALDH1A1 (0.50) | GAAMETAP2ALDH1A1HPGDALOX15 | |
| SCHEMBL57324 | 0.72 | ALDH1A1 (0.50) | GAAMETAP2ALDH1A1HPGDALOX15 | |
| SCHEMBL25191881 | 0.72 | AR (0.44) | ARGAAALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456793-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | Equistar Chemicals, LP (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011040-A1 | CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS | EQUISTAR CHEMICALS, LP (US) | 2011-01-27 | — | — | WO | disclosed |