Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367320 | 0.88 | ALDH1A1 (0.35) | ALDH1A1LMNAMEN1PABPC1KMT2A | |
| SCHEMBL9368918 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL9364454 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1PABPC1KMT2A | |
| SCHEMBL9364000 | 0.79 | TSHR (0.41) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9363575 | 0.79 | PKM (0.51) | ALDH1A1SCDPOLBADORA2API4KA | |
| SCHEMBL3877845 | 0.75 | PDE4B (0.43) | ALDH1A1KDM4ECDK2MAPT | |
| SCHEMBL3452770 | 0.74 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1PABPC1KMT2A | |
| SCHEMBL1951450 | 0.74 | ALDH1A1 (0.42) | ALDH1A1LMNAMEN1PABPC1KMT2A | |
| SCHEMBL9668607 | 0.73 | KDM4E (0.35) | ALDH1A1KMT2ARAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL9368942 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464112-B1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | GEA FARMACEUTISK FABRIK AS (DK) | 1994-10-05 | — | — | EP | disclosed |
| US-5223619-A | Catalytic cyclization | A/S GEA FARMACEUTISK FABRIK (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | disclosed |
| WO-1990011283-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | A/S GEA FARMACEUTISK FABRIK (DK) | 1990-10-04 | — | — | WO | disclosed |