Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368918 | 0.76 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2GAAPKMMAPT | |
| SCHEMBL3877845 | 0.74 | PDE4B (0.43) | KDM4EALDH1A1GAAPKMTSHR | |
| SCHEMBL9364010 | 0.73 | ALDH1A1 (0.36) | KDM4EALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL9915083 | 0.66 | SMN1; SMN2 (0.57) | KDM4EALDH1A1SMN1; SMN2GAATSHR | |
| SCHEMBL9363575 | 0.65 | PKM (0.51) | ALDH1A1GAAPKMTSHRPOLB | |
| SCHEMBL9367333 | 0.64 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTL3MBTL1GAA | |
| SCHEMBL1356859 | 0.64 | MAPT (0.48) | KDM4EALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL9915111 | 0.63 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL3452770 | 0.63 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9367320 | 0.63 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2GAAKMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | disclosed |