Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15210209 | 0.93 | TSHR (0.46) | LTA4HNPC1GLARAB9ASMN1; SMN2 | |
| SCHEMBL9021032 | 0.83 | LTA4H (0.56) | LTA4HPLA2G2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5755407 | 0.78 | THRB (0.38) | SMN1; SMN2TSHRTBXAS1THRBALDH1A1 | |
| SCHEMBL22315192 | 0.75 | TBXAS1 (0.62) | LTA4HTBXAS1ALDH1A1CACNA1BKMT2A | |
| SCHEMBL1729305 | 0.73 | MCHR1 (0.45) | LTA4HNPC1RAB9ASMN1; SMN2TBXAS1 | |
| SCHEMBL28093430 | 0.73 | HTT (0.57) | SMN1; SMN2TSHRALDH1A1MEN1LMNA | |
| SCHEMBL9364537 | 0.73 | LTA4H (0.47) | LTA4HPLA2G2ANPC1GLARAB9A | |
| SCHEMBL7008972 | 0.70 | NOTUM (0.56) | LTA4HNPC1GLARAB9ASMN1; SMN2 | |
| SCHEMBL3519967 | 0.70 | MAPT (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1563130 | 0.69 | TSHR (0.48) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388665-B1 | Substituted N-hydroxypyrazoles and N-hydroxy-triazoles and their use in combatting parasites | BASF AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| US-5173501-A | Nematocides, insecticides | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5120756-A | Insecticides, nematocides; antifertility agents | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |