Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441610 | 1.00 | SIRT1 (0.38) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL2877170 | 0.86 | GAA (0.43) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL2877169 | 0.86 | GAA (0.43) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL2877172 | 0.86 | GAA (0.43) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL8627333 | 0.85 | GAA (0.43) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| Potassium SCHEMBL8627342 | 0.85 | GAA (0.43) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| Potassium Ion SCHEMBL8627336 | 0.84 | HDAC3 (0.39) | SIRT1NPC1RAB9ASMN1; SMN2HDAC3 | |
| SCHEMBL8443325 | 0.83 | PI4KB (0.39) | SIRT1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8441965 | 0.83 | LMNA (0.40) | SIRT1HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL10978294 | 0.83 | LMNA (0.40) | SIRT1HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594263-A1 | Thioalkylthio cephalosporin derivatives and intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |