Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9083564 | 0.90 | DRD4 (0.51) | SIGMAR1HTR1AHTR7 | |
| SCHEMBL9364073 | 0.89 | HTR1A (0.47) | SIGMAR1KCNH2HTR1AHTR7 | |
| SCHEMBL9364264 | 0.87 | HTR7 (0.53) | KCNH2USP2ALDH1A1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9083376 | 0.86 | HTR7 (0.52) | KCNH2USP2ALDH1A1HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL9083559 | 0.84 | HTR7 (0.55) | HTR1AHTR7 | |
| SCHEMBL30767216 | 0.76 | KCNH2 (0.90) | SIGMAR1KCNH2HTR1AHTR7 | |
| SCHEMBL27715320 | 0.76 | KCNH2 (0.72) | SIGMAR1KCNH2HTR1AHTR7L3MBTL1 | |
| SCHEMBL8844829 | 0.75 | KCNA3 (0.46) | ALDH1A1LMNATP53MAPT | |
| Hydrochloric Acid SCHEMBL7658247 | 0.75 | KCNH2 (0.88) | SIGMAR1KCNH2HTR1AHTR7 | |
| SCHEMBL4524281 | 0.73 | KCNH2 (1.00) | KCNH2ALDH1A1HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512525-B1 | Carbostyril derivatives and pharmaceutical compositions containing the same for use as a disturbance-of-consciousness improving agent, central nervous system stimulant or sigma receptor agonist | OTSUKA PHARMA CO LTD (JP) | 1994-11-30 | — | — | EP | claimed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | SIGMAR1 201/4885KCNH2 3934/4885USP2 3072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.