Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402587 | 0.89 | ALDH1A1 (0.46) | CA1CA2MAPTLMNAKMT2A | |
| SCHEMBL8743220 | 0.81 | CES2 (0.48) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL2534978 | 0.81 | CES2 (0.48) | CES2CES1CA1CA2PTPRF | |
| SCHEMBL593134 | 0.80 | CA1 (0.56) | CA1CA2HPGDMAPTSMN1; SMN2 | |
| SCHEMBL22191623 | 0.80 | TSHR (0.55) | CES2CES1CA1CA2MAPT | |
| SCHEMBL15846817 | 0.78 | LMNA (0.52) | RAB9ANPC1MAPTLMNAKMT2A | |
| SCHEMBL9630702 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL10050028 | 0.78 | TDP1 (0.59) | CES2CES1RAB9ANPC1HPGD | |
| SCHEMBL1377357 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2RAB9A | |
| Benzene SCHEMBL28103328 | 0.77 | LMNA (0.58) | CES2CES1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573912-A | Automobile air outlet thumb wheel with fluorescent function and production process thereof | 常州市佳乐车辆配件制造有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-108101856-B | Preparation method of acyl-substituted pyrazine compound | HENAN AGRICULTURAL UNIVERSITY (CN) | 2019-12-10 | — | — | CN | claimed |
| CN-114956927-B | Preparation method of beta-halogenated olefine acid ester derivative | 南通大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-113583988-B | Amino acid dehydrogenase mutant and application thereof | 沈阳药科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-115584518-A | Electrochemical method for preparing N-alkylamide | 桂林理工大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-111978201-B | Synthesis method of N, N' -diaryl benzoyl hydrazine compound | 甘肃农业大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-111662202-B | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-114956927-A | Preparation method of beta-halogenated olefine acid ester derivative | 南通大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114573912-A | Automobile air outlet thumb wheel with fluorescent function and production process thereof | 常州市佳乐车辆配件制造有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113583988-A | Amino acid dehydrogenase mutant and application thereof | 沈阳药科大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-105330628-B | Method for preparing 4-hydroxy butenolide from keto acid and alkyne | 苏州大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-109232282-B | Synthetic method of 2-aminobenzophenone compound | 新乡医学院 | 2021-03-02 | — | — | CN | disclosed |
| CN-111662202-A | Synthetic method of alpha-ketoamide compound | 五邑大学 | 2020-09-15 | — | — | CN | disclosed |
| CN-111065623-A | Linker for antibody drug conjugates | 德克萨斯州大学系统董事会 | 2020-04-24 | — | — | CN | disclosed |
| EP-0469045-B1 | SYNTHETIC $i(PSEUDOMONAS) $i(AERUGINOSA) PILIN PEPTIDE AND RELATED VACCINES AND DIAGNOSTICS | UNIV ALBERTA (CA) | 1994-06-15 | — | — | EP | disclosed |
| EP-0119705-B1 | OCTAPEPTIDE VASOPRESSIN ANTAGONISTS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-09-06 | — | — | EP | disclosed |