Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2402587 | 0.89 | ALDH1A1 (0.46) | CA1CA2MAPTMEN1KMT2A | |
| Fluorobenzene SCHEMBL28196684 | 0.86 | PLA2G7 (0.50) | CES2CES1NPC1RAB9AMAPT | |
| SCHEMBL7868516 | 0.81 | RAB9A (0.49) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL2835113 | 0.81 | CES2 (0.48) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL593134 | 0.80 | CA1 (0.56) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL22191623 | 0.80 | TSHR (0.55) | CES2CES1CA1CA2MAPT | |
| SCHEMBL248548 | 0.79 | CES2 (0.62) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL15846817 | 0.78 | LMNA (0.52) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9364286 | 0.78 | CES2 (0.50) | CES2CES1CA1CA2NPC1 | |
| SCHEMBL10050028 | 0.78 | TDP1 (0.59) | CES2CES1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333560-B | Method for preparing spiro beta-lactam | 合肥工业大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-114409602-A | Method for synthesizing alpha-keto acid by using oxalyl chloride and Grignard reagent as raw materials | 武汉大学 | 2022-04-29 | — | — | CN | disclosed |
| CN-105330628-B | Method for preparing 4-hydroxy butenolide from keto acid and alkyne | 苏州大学 | 2021-10-26 | — | — | CN | disclosed |
| CN-106279023-B | 3,4, 5-trisubstituted pyrazole compound, preparation method, pharmaceutical composition and application | 中国科学院上海药物研究所 | 2021-06-22 | — | — | CN | disclosed |
| CN-107337581-B | Process for preparing difluoroalcohol compounds | 三和涂料工业有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-111978201-A | Synthesis method of N, N' -diaryl benzoyl hydrazine compound | 甘肃农业大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-108017635-A | A kind of method of successive reaction synthesizing aryl benzoquinolizine ketone compounds | 黑龙江大学 | 2018-05-11 | — | — | CN | disclosed |
| CN-107337581-A | The method for preparing two fluoro alcoholic compounds | 三和涂料工业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0480918-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | disclosed |
| EP-0480918-A4 | REDUCED SIZE LHRH ANALOGS. | ABBOTT LAB (US) | 1991-06-04 | — | — | EP | disclosed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989007451-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |
| US-4255594-A | Hydrogenation of halogen-containing carboxylic anhydrides | ALLIED CHEMICAL CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |