Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825348 | 1.00 | LPAR2 (0.48) | LPAR2LPAR3TRPA1TRPM8HTT | |
| SCHEMBL9364381 | 0.83 | LPAR2 (0.63) | LPAR2LPAR3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9364375 | 0.83 | LPAR2 (0.63) | LPAR2LPAR3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7825350 | 0.82 | MAPT (0.47) | TRPA1TRPM8HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7833348 | 0.77 | ALDH1A1 (0.62) | LPAR2LPAR3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7833350 | 0.77 | ALDH1A1 (0.62) | LPAR2LPAR3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29621571 | 0.72 | TSHR (0.52) | TRPA1SMN1; SMN2ALDH1A1CYP2C9POLB | |
| SCHEMBL211283 | 0.72 | TSHR (0.52) | TRPA1SMN1; SMN2ALDH1A1CYP2C9POLB | |
| SCHEMBL8063995 | 0.71 | TRPA1 (0.63) | TRPA1TRPM8SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL8063998 | 0.71 | TRPA1 (0.63) | TRPA1TRPM8SMN1; SMN2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |