Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901893 | 0.85 | ALOX5 (0.58) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL9364600 | 0.83 | MEN1 (0.70) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL9368109 | 0.80 | MAPT (0.64) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL30383463 | 0.80 | MAPT (0.64) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL9368101 | 0.80 | MAPT (0.64) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL6653306 | 0.78 | MAPT (0.60) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL11584099 | 0.78 | MEN1 (0.54) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL3953509 | 0.77 | ALOX5 (0.56) | MEN1NR1I2LMNAPGRADRB2 | |
| SCHEMBL9364616 | 0.77 | ALDH1A1 (0.40) | MAPTKMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL10540515 | 0.76 | HPGD (0.55) | MEN1NR1I2LMNAPGRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412803-B1 | Chalcone derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5089654-A | Antiulcer agents | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0412803-A1 | Chalcone derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1991-02-13 | — | — | EP | disclosed |