Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364600 | 0.91 | MEN1 (0.70) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL3953509 | 0.91 | ALOX5 (0.56) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6653306 | 0.89 | MAPT (0.60) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL11584099 | 0.89 | MEN1 (0.54) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL10540515 | 0.86 | HPGD (0.55) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL5519287 | 0.86 | MAOB (0.53) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6432997 | 0.86 | MAOB (0.64) | HPGDMAOBALDH1A1 | |
| SCHEMBL9364602 | 0.85 | MEN1 (0.51) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL6652397 | 0.81 | ALOX5 (0.53) | ALOX5MAPTHPGDMEN1NR1I2 | |
| SCHEMBL5384385 | 0.81 | MAOB (0.55) | ALOX5MAPTHPGDMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | claimed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | claimed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | claimed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | claimed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-09-17 | — | — | US | disclosed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-1768945-B1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-1768945-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006003010-A1 | SUBSTITUTED HYDROXYACETOPHENON DERIVATIVES | RIEMSER ARZNEIMITTEL AG (DE) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234023-A1 | SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES | GNPAT, HOGA1, NQO1 | ALOX5 570/4885MAPT 2828/4885HPGD 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.