Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ACP1 | P24666 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692960 | 0.83 | GPR35 (0.74) | GPR35MAPTACP1LMNAP2RX1 | |
| SCHEMBL14263848 | 0.82 | ALDH1A1 (0.65) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL9364645 | 0.79 | GPR35 (0.68) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL17494177 | 0.78 | GPR35 (0.92) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL16628091 | 0.76 | LMNA (0.71) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL2161415 | 0.76 | MAPT (0.67) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL5773763 | 0.76 | MAPT (0.67) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL2681462 | 0.75 | MAPT (0.78) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL11788448 | 0.74 | MAPT (0.63) | GPR35MAPTACP1LMNAALDH1A1 | |
| SCHEMBL5833345 | 0.74 | GPR35 (0.66) | GPR35MAPTACP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377112-B1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK AS (DK) | 1994-08-24 | — | — | EP | disclosed |
| US-5061706-A | 2,3-QUINOXALINEDIONES FOR USE AS NEUROLEPTICS | NOVO NORDISK A/S (DK) | 1991-10-29 | — | — | US | disclosed |
| EP-0377112-A1 | Quinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1990-07-11 | — | — | EP | disclosed |