Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365053 | 0.92 | EPHX1 (0.46) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9360593 | 0.89 | HSD17B10 (0.36) | ALDH1A1SIRT5PPARGPPARANR1H4 | |
| SCHEMBL9366309 | 0.89 | ALOX5 (0.43) | ALDH1A1PPARGPPARAALOX5MAPT | |
| SCHEMBL9361483 | 0.88 | ALDH1A1 (0.44) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9361488 | 0.88 | ALDH1A1 (0.44) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9365795 | 0.87 | ALDH1A1 (0.43) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9365802 | 0.87 | ALDH1A1 (0.43) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9365772 | 0.84 | EPHX1 (0.48) | ALDH1A1EPHX1SIRT5PPARGPPARA | |
| SCHEMBL9361154 | 0.81 | CYP1A2 (0.44) | ALDH1A1PPARGPPARAALOX5MAPT | |
| SCHEMBL9361205 | 0.81 | HSD17B10 (0.38) | ALDH1A1EPHX1SIRT5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |