Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9361154 | 0.93 | CYP1A2 (0.44) | ALOX5PPARGPPARACYP1A2KDM4E | |
| SCHEMBL9364858 | 0.89 | ALDH1A1 (0.47) | ALOX5PPARGPPARAMAPTALDH1A1 | |
| SCHEMBL9361229 | 0.89 | ALOX5 (0.41) | ALOX5PPARGPPARACYP1A2KDM4E | |
| SCHEMBL9361232 | 0.89 | ALOX5 (0.41) | ALOX5PPARGPPARACYP1A2KDM4E | |
| SCHEMBL9360593 | 0.88 | HSD17B10 (0.36) | ALOX5PPARGPPARAKDM4ELMNA | |
| SCHEMBL9361195 | 0.88 | PPARG (0.40) | ALOX5PPARGPPARACYP1A2KDM4E | |
| SCHEMBL9361202 | 0.88 | PPARG (0.40) | ALOX5PPARGPPARACYP1A2KDM4E | |
| SCHEMBL9365339 | 0.85 | KDM4E (0.43) | ALOX5CYP1A2KDM4ENPC1LMNA | |
| SCHEMBL9365053 | 0.81 | EPHX1 (0.46) | PPARGPPARALMNAMAPTALDH1A1 | |
| SCHEMBL9365831 | 0.81 | CYP1A2 (0.40) | ALOX5PPARGPPARACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418038-B1 | Naphthalene derivative and preparation method thereof | TEIJIN LTD (JP) | 1994-04-20 | — | — | EP | disclosed |
| US-5149859-A | Cardiovascular disorders | TEIJIN LIMITED (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0418038-A1 | Naphthalene derivative and preparation method thereof | TEIJIN LIMITED (JP) | 1991-03-20 | — | — | EP | disclosed |