Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936354 | 0.80 | STAT3 (0.46) | MAPTSTAT3GPR84POLB | |
| SCHEMBL3396574 | 0.78 | STAT3 (0.74) | ALDH1A1MAPTSTAT3SMN1; SMN2CYP1A2 | |
| SCHEMBL1660158 | 0.76 | CYP1A2 (0.61) | ALDH1A1TDP1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL936239 | 0.75 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2GPR84KDM4E | |
| SCHEMBL935586 | 0.75 | POLB (0.51) | ALDH1A1MAPTGPR84KDM4EPOLB | |
| SCHEMBL6287959 | 0.74 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPTSMN1; SMN2GPR84 | |
| SCHEMBL935459 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2GPR84KMT2A | |
| SCHEMBL936096 | 0.73 | GPR84 (0.41) | ALDH1A1MAPTSMN1; SMN2GPR84KDM4E | |
| SCHEMBL936027 | 0.73 | GPR84 (0.42) | MAPTGPR84KMT2AKDM4EPOLB | |
| SCHEMBL955533 | 0.73 | GPR84 (0.41) | ALDH1A1TDP1MAPTGPR84KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011010748-A1 | INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE | 味の素株式会社 (JP) | 2011-01-27 | — | — | WO | disclosed |