Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582882 | 0.84 | ALOX5 (0.52) | ALOX5GRM5EGLN1 | |
| SCHEMBL9582290 | 0.80 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL9365005 | 0.77 | MAOB (0.30) | ALOX5 | |
| SCHEMBL9370985 | 0.76 | ALOX5 (0.41) | ALOX5GRM5 | |
| SCHEMBL9356426 | 0.74 | ALOX5 (0.41) | ALOX5FFAR1GRM5EGLN1 | |
| SCHEMBL9365968 | 0.74 | ALOX5 (0.44) | ALOX5FFAR1 | |
| SCHEMBL9022255 | 0.74 | ALOX5 (0.58) | ALOX5GRM5 | |
| SCHEMBL9582257 | 0.72 | MAOA (0.36) | ALOX5 | |
| SCHEMBL9582268 | 0.72 | MAOA (0.36) | ALOX5 | |
| SCHEMBL9365123 | 0.71 | ALOX5 (0.51) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375457-B1 | Cyclic ether derivatives | ICI PLC (GB) | 1994-03-16 | — | — | EP | disclosed |
| US-5219881-A | Enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-15 | — | — | US | disclosed |
| US-5098932-A | Inhibitors of lipoxygenase for treatment of diseases mediated with leukotrienes | IMPERIAL CHEMICAL INDUSTRIES PLC, ICI PHARMA (FR) | 1992-03-24 | — | — | US | disclosed |