Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365375 | 1.00 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9365441 | 0.90 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9365446 | 0.90 | LMNA (0.54) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9365675 | 0.89 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9365679 | 0.89 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9366482 | 0.88 | LMNA (0.52) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9366481 | 0.88 | LMNA (0.52) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9366567 | 0.88 | LMNA (0.52) | ALDH1A1LMNAMEN1KMT2AHPGD | |
| SCHEMBL9365498 | 0.86 | LMNA (0.48) | ALDH1A1LMNAMEN1KMT2AGPR183 | |
| SCHEMBL9366552 | 0.86 | ALDH1A1 (0.48) | ALDH1A1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | claimed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | claimed |
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |